I believe that as of Workbooks 1.3 you can just
#r /path/to/your/integration.dll, and each time you rerun the
#r cell it will be reloaded. So you could point directly to your build output.
I'll ask somebody more familiar with the SDK stuff to take a look tomorrow.
I'll have to look into this next week, sorry for the delay.
Unfortunately, this fix was not approved for backporting.
If you do disable Lightweight Solution Load, and the bug still occurs, please let me know, as that could indicate it's actually a new bug.
Thank you for filing a bug. We are looking at some other property grid changes so it is now being tracked.
If you are using the latest stable Xamarin (22.214.171.1243, check
Help -> About Microsoft Visual Studio to confirm), Android and iOS inspection is known to be broken. See https://bugzilla.xamarin.com/show_bug.cgi?id=56232.
A fix is targeted to go out soon with the 15.2.2 update of VS 2017.
Typically, if you see the button being disabled, you can check the log file for any interesting output. My guess is that you will see the same error as in the above bug report.
For more "normal" error conditions, the button remains enabled, and clicking on it will give you a dialog letting you know what you have to do to get Inspector to work with your project.