If you create a single view application with Visual Studio, you'll get a slightly different project from an application created by Xamarin Studio. For example, VS gives you MainStoryboard.storyboard and XS gives you Main.storyboard. VS gives you RootViewController.cs and XS gives you ViewController.cs. For what it's worth, a single view Swift application created by Xcode gives Main.storyboard and ViewController.swift.
Why do VS and XS create slightly different projects?