I've tried to research the potential for development issue (i.e. using VS / Xamarin) on Big Sur / M1 processors, or for application issues (i.e. from the users side), but - I guess because it's still very much 'early days' - can't find any reports of problems. Purchasing a new M1-based machine is a non-trivial investment just to 'try and see', so I was wondering if Xamarin for Mac developers might have any first-hand experience in this area, or perhaps the Xamarin team might have some information to share.
FWIW, our Xamarin-developed Mac application (that we developed on Catalina / Intel processors), seems to work just fine on Big Sur / Intel, or at least we haven't found any problems and none of our users have so far either.